Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12210784 | 0.76 | HDAC6 (0.64) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12210946 | 0.74 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12211016 | 0.72 | HDAC6 (0.44) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL2522196 | 0.71 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12211089 | 0.71 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12210803 | 0.70 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12210759 | 0.68 | GRM1 (0.44) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL2519323 | 0.68 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12211086 | 0.68 | HDAC6 (0.47) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12210979 | 0.64 | HDAC6 (0.62) | HDAC6HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130163-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |