Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 19/20 | 0.68 |
| ▸ | CSNK2A1 | P68400 | 19/20 | 0.68 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635298 | 0.86 | CSNK2A2 (0.68) | CSNK2A2CSNK2A1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL14635296 | 0.86 | CSNK2A2 (0.68) | CSNK2A2CSNK2A1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL14635449 | 0.81 | CSNK2A2 (1.00) | CSNK2A2CSNK2A1 | |
| SCHEMBL14634717 | 0.81 | CSNK2A2 (1.00) | CSNK2A2CSNK2A1 | |
| SCHEMBL14634716 | 0.81 | CSNK2A2 (1.00) | CSNK2A2CSNK2A1 | |
| SCHEMBL14634973 | 0.78 | CSNK2A2 (0.93) | CSNK2A2CSNK2A1 | |
| SCHEMBL14635247 | 0.78 | CSNK2A2 (1.00) | CSNK2A2CSNK2A1 | |
| SCHEMBL14634971 | 0.78 | CSNK2A2 (0.93) | CSNK2A2CSNK2A1 | |
| SCHEMBL12284249 | 0.78 | CSNK2A2 (1.00) | CSNK2A2CSNK2A1 | |
| SCHEMBL14634987 | 0.78 | CSNK2A2 (1.00) | CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123493-A1 | SUBSTITUTED PYRROLOTRIAZINES AS PROTEIN KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-10-06 | — | — | WO | disclosed |