Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737797 | 0.93 | POLB (0.63) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL5962552 | 0.91 | CA12 (0.54) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL13989319 | 0.89 | GAA (0.73) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL826066 | 0.88 | HDAC3 (0.64) | GAAATMMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6029960 | 0.86 | GAA (0.59) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL13652580 | 0.86 | GAA (0.59) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL21367518 | 0.85 | MAPK14 (0.51) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL13002983 | 0.85 | GAA (0.63) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL1189878 | 0.84 | CA12 (0.59) | GAAPOLBATMMAPTSMN1; SMN2 | |
| SCHEMBL10117151 | 0.84 | POLB (0.60) | GAAPOLBATMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288462-B2 | Polyolefin resin composition | ADEKA CORPORATION (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110218279-A1 | POLYOLEFIN RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |