Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194292 | 0.93 | PDPK1 (0.81) | PDPK1 | |
| SCHEMBL10193555 | 0.89 | PDPK1 (0.81) | PDPK1 | |
| SCHEMBL2621928 | 0.89 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL12286125 | 0.87 | PDPK1 (0.77) | PDPK1 | |
| SCHEMBL2621923 | 0.85 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2631926 | 0.83 | PDPK1 (0.80) | PDPK1 | |
| SCHEMBL10193450 | 0.82 | PDPK1 (0.81) | PDPK1 | |
| SCHEMBL2621930 | 0.80 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2632100 | 0.80 | PDPK1 (0.79) | PDPK1 | |
| SCHEMBL2631998 | 0.79 | PDPK1 (0.83) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011131741-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDES AS PDK1 INIHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-27 | — | — | WO | disclosed |