Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MST1R | Q04912 | 19/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14860655 | 1.00 | MST1R (0.51) | MST1RNTRK1METKITAXL | |
| SCHEMBL14860656 | 1.00 | MST1R (0.51) | MST1RNTRK1METKITAXL | |
| SCHEMBL16177098 | 0.93 | MST1R (0.53) | MST1RNTRK1METKITAXL | |
| SCHEMBL2537112 | 0.91 | MST1R (0.55) | MST1RNTRK1METKITAXL | |
| SCHEMBL2537111 | 0.91 | MST1R (0.55) | MST1RNTRK1METKITAXL | |
| SCHEMBL14860042 | 0.91 | MST1R (0.55) | MST1RNTRK1METKITAXL | |
| SCHEMBL14871772 | 0.86 | MST1R (0.54) | MST1RNTRK1METKITAXL | |
| SCHEMBL14871596 | 0.85 | MST1R (0.56) | MST1RNTRK1METKITAXL | |
| SCHEMBL12252032 | 0.85 | MST1R (0.56) | MST1RNTRK1METKITAXL | |
| SCHEMBL16176857 | 0.85 | MST1R (0.56) | MST1RNTRK1METKITAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906852-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2014-12-09 | — | — | US | disclosed |
| WO-2011127567-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2011-10-20 | — | — | WO | disclosed |