Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | TP53 | P04637 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707908 | 0.92 | MAPT (0.65) | RXFP1MAPTTP53POLBTDP1 | |
| SCHEMBL12286110 | 0.88 | RXFP1 (0.78) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12285625 | 0.88 | RXFP1 (0.70) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12285304 | 0.88 | RXFP1 (0.77) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12286048 | 0.88 | RXFP1 (0.70) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12286049 | 0.87 | RXFP1 (0.74) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12286687 | 0.87 | RXFP1 (0.71) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12286025 | 0.87 | RXFP1 (0.71) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12287163 | 0.87 | RXFP1 (0.75) | RXFP1MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL12286109 | 0.86 | RXFP1 (0.77) | RXFP1MAPTTP53SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927561-B2 | Pyrimidinedione anti-viral compounds | Kineta, Inc. (US) | 2015-01-06 | — | — | US | disclosed |
| WO-2011133722-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | WO | disclosed |