Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 9/20 | 0.78 |
| ▸ | MAPT | P10636 | 8/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285491 | 0.91 | RXFP1 (1.00) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL12286377 | 0.89 | TP53 (0.73) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL14707921 | 0.89 | TP53 (0.84) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL12286213 | 0.88 | POLB (0.79) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL12286280 | 0.88 | POLB (0.79) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL12285854 | 0.88 | TP53 (0.84) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL12285852 | 0.87 | TP53 (0.86) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL12286278 | 0.87 | RXFP1 (0.86) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL14707928 | 0.87 | TP53 (0.74) | RXFP1TDP1TP53MAPTPOLB | |
| SCHEMBL14707922 | 0.86 | TP53 (0.73) | RXFP1TDP1TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927561-B2 | Pyrimidinedione anti-viral compounds | Kineta, Inc. (US) | 2015-01-06 | — | — | US | disclosed |
| WO-2011133722-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | WO | disclosed |