SCHEMBL12290808

SCHEMBL12290808

C=NNNC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17444796 0.72
SCHEMBL469416 0.67
SCHEMBL16221601 0.58
SCHEMBL14370574 0.58
SCHEMBL6951658 0.58
SCHEMBL22091 0.52
SCHEMBL16072423 0.48
SCHEMBL12730599 0.48
SCHEMBL14642132 0.48
Hydrochloric Acid SCHEMBL743762 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210388359-A1 OLIGONUCLEOTIDE FORMULATION METHOD ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2021-12-16 US disclosed
WO-2020198466-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. (US) 2020-10-01 WO disclosed
EP-3029454-B1 METHOD FOR EVALUATING HARDNESS OF POLYMER MATERIAL SUMITOMO RUBBER IND (JP) 2018-03-14 EP disclosed
US-20170020862-A1 INTRANASAL NALTREXONE 3B PHARMACEUTICALS INC (US) 2017-01-26 US disclosed
US-20160122400-A1 POLYPEPTIDES WITH PERMEASE ACTIVITY DSM IP ASSETS B.V. (NL) 2016-05-05 US disclosed
US-20160068441-A1 HIGH CORDIERITE-TO-MULLITE RATIO CORDIERITE-MULLITE-ALUMINUM MAGNESIUM TITANATE COMPOSITIONS AND CERAMIC ARTICLES COMPRISING SAME CORNING INCORPORATED 2016-03-10 US disclosed
EP-2918338-A1 Process for the production of 1,3-butadiene LANXESS Deutschland GmbH (DE) 2015-09-16 EP disclosed
US-20140171458-A1 INTRANASAL NALTREXONE 3B PHARMACEUTICALS, INC. (US) 2014-06-19 US disclosed
US-20120251453-A1 Methods and Compositions Related to Annexin 1-Binding Compounds SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2012-10-04 US disclosed
EP-2368877-A1 Chiral intermediates for the preparation of peptidomimetic protease inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-09-28 EP disclosed
EP-2368878-A1 Peptidomimetic protease inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-09-28 EP disclosed
US-20110118447-A1 METHODS AND MATERIALS FOR TARGETED AFFINITY ENHANCEMENT XOMA TECHNOLOGY LTD. (US) 2011-05-19 US disclosed
US-20070027156-A1 Crf antagonists and heterobicyclic compounds ONO PHARMACEUTICAL CO., LTD. (JP) 2007-02-01 US disclosed