Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1227053 | 0.91 | GAA (0.44) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL1227005 | 0.90 | GAA (0.43) | GAACCR1POLBTSHRKDM4E | |
| SCHEMBL1228685 | 0.88 | GAA (0.42) | GAACCR1POLBTSHRKDM4E | |
| SCHEMBL1228580 | 0.87 | GAA (0.44) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL121172 | 0.87 | GAA (0.50) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL13523714 | 0.87 | GAA (0.50) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL1227001 | 0.87 | GAA (0.42) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL1879570 | 0.86 | GAA (0.49) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL1228467 | 0.86 | CCR1 (0.40) | GAACCR1LMNAPOLBTSHR | |
| SCHEMBL20801744 | 0.86 | GAA (0.51) | GAACCR1LMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464643-A1 | MICROBIOCIDAL HETEROCYCLES | Syngenta Participations AG (CH) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018401-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-02-17 | — | — | WO | disclosed |