Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560382 | 0.89 | PIM1 (0.45) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1560384 | 0.89 | PIM1 (0.45) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1560150 | 0.88 | PIM1 (0.41) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1558935 | 0.88 | PIM1 (0.41) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1560153 | 0.88 | PIM1 (0.41) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1558937 | 0.88 | PIM1 (0.41) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL13496628 | 0.82 | PIM1 (0.39) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1560336 | 0.81 | PIM1 (0.42) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1560331 | 0.81 | PIM1 (0.42) | PIM1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL2834480 | 0.77 | PIM1 (0.69) | PIM1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224242-A1 | STYRLYQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2011-09-15 | — | — | US | disclosed |
| US-20110224242-A1 | STYRLYQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2011-09-15 | — | — | US | disclosed |
| US-20100120847-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100120847-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-05-13 | — | — | US | disclosed |
| WO-2010010149-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147912-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120847-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | POLQ, PARP1, PARP14 | PIM1 19/4885MAPT 1159/4885KDM4E 501/4885 |
| US-20110224242-A1 | STYRLYQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | POLQ, POLB, TYMP | PIM1 35/4885MAPT 1980/4885KDM4E 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.