Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537085 | 0.86 | GABRR1 (0.46) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL16626924 | 0.86 | GABRR1 (0.46) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL11193240 | 0.86 | GABRR1 (0.46) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL5518553 | 0.86 | GABRR1 (0.46) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL20088918 | 0.83 | ACE2 (0.38) | GABRR1CYP1A2TSHRFOLH1NAALAD2 | |
| SCHEMBL20088923 | 0.83 | ACE2 (0.38) | GABRR1CYP1A2TSHRFOLH1NAALAD2 | |
| SCHEMBL20088920 | 0.83 | ACE2 (0.38) | GABRR1CYP1A2TSHRFOLH1NAALAD2 | |
| SCHEMBL12344066 | 0.80 | TDP1 (0.39) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL20088915 | 0.78 | TDP1 (0.37) | GABRR1CYP1A2TSHR | |
| SCHEMBL20088917 | 0.78 | TDP1 (0.37) | GABRR1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106639-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2011-09-01 | — | — | WO | disclosed |