Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344514 | 0.82 | SLC6A2 (0.51) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14457485 | 0.82 | SLC6A2 (0.51) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14457487 | 0.82 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20344464 | 0.82 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28278036 | 0.80 | MEN1 (0.49) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28278014 | 0.79 | CHRNA7 (0.44) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28279416 | 0.78 | KCNH2 (0.46) | LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL28279402 | 0.78 | KCNH2 (0.46) | LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL28279411 | 0.77 | PPARG (0.49) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31000123 | 0.76 | CHRNA7 (0.57) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113859-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2011-09-22 | — | — | WO | disclosed |