Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | FNTA | P49354 | 3/20 | 0.50 |
| ▸ | FNTB | P49356 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | SQLE | Q14534 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155127 | 0.86 | KDM4E (0.55) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL2928302 | 0.86 | KDM4E (0.55) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL2928304 | 0.86 | KDM4E (0.55) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL11466302 | 0.83 | KMT2A (0.71) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL11466301 | 0.83 | KMT2A (0.71) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL31488021 | 0.80 | KDM4E (0.33) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL10045726 | 0.79 | KMT2A (0.60) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL31659057 | 0.79 | KMT2A (0.60) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL31659048 | 0.79 | KMT2A (0.60) | KMT2AALOX15MEN1CYP3A4KDM4E | |
| SCHEMBL31659059 | 0.79 | KMT2A (0.60) | KMT2AALOX15MEN1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543437-A2 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011108672-A2 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | 高砂香料工業株式会社 (JP) | 2011-09-09 | — | — | WO | disclosed |