⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295245 | 1.00 | — | — | |
| SCHEMBL12295234 | 1.00 | — | — | |
| SCHEMBL15002703 | 1.00 | — | — | |
| SCHEMBL21242710 | 1.00 | — | — | |
| SCHEMBL14819886 | 1.00 | — | — | |
| SCHEMBL887967 | 0.83 | — | — | |
| SCHEMBL22778050 | 0.83 | — | — | |
| SCHEMBL887968 | 0.83 | — | — | |
| SCHEMBL29858530 | 0.80 | TP53 (0.47) | — | |
| SCHEMBL21673293 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098232-A1 | Multicyclic Peptides and Methods for Their Preparation | UNIVERSITEIT VAN AMSTERDAM (NL) | 2022-03-31 | — | — | US | disclosed |
| US-11192918-B2 | Multicyclic peptides and methods for their preparation | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2021-12-07 | — | — | US | disclosed |
| US-20200239516-A1 | Multicyclic Peptides and Methods for Their Preparation | UNIVERSITEIT VAN AMSTERDAM (NL) | 2020-07-30 | — | — | US | disclosed |
| EP-3551642-A1 | MULTICYCLIC PEPTIDES AND METHODS FOR THEIR PREPARATION | Stichting voor de Technische Wetenschappen (NL) | 2019-10-16 | — | — | EP | disclosed |
| EP-2758426-B1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK AS (DK) | 2019-08-07 | — | — | EP | disclosed |
| WO-2018106112-A1 | MULTICYCLIC PEPTIDES AND METHODS FOR THEIR PREPARATION | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2018-06-14 | — | — | WO | disclosed |
| WO-2011117416-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2011-09-29 | — | — | WO | disclosed |