SCHEMBL12295358

SCHEMBL12295358

CCC(O)C[18F]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12821067 1.00
SCHEMBL17929593 1.00
SCHEMBL2118344 1.00
Hydrochloric Acid SCHEMBL9232187 0.96
SCHEMBL18277107 0.83
SCHEMBL25557 0.79
3-Pentanol SCHEMBL5341 0.79
SCHEMBL9946205 0.76
SCHEMBL9945693 0.76
3-Pentanol SCHEMBL3183384 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8013161-B1 Fluoroalkyl tetrabenazine carbinol compounds as imaging agents and probes GENERAL ELECTRIC COMPANY (US) 2011-09-06 US disclosed
US-20110206609-A1 FLUOROALKYL TETRABENAZINE CARBINOL COMPOUNDS AS IMAGING AGENTS AND PROBES GENERAL ELECTRIC COMPANY (US) 2011-08-25 US disclosed
US-7919622-B2 Intermediates for fluorinated tetrabenazine carbinol compounds imaging agents and probes GENERAL ELECTRIC COMPANY 2011-04-05 US disclosed
US-7910738-B2 Intermediates for alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes GENERAL ELECTRIC COMPANY (US) 2011-03-22 US disclosed
US-7897769-B2 Intermediates for fluorinated dihydrotetrabenazine ether imaging agents and probes GENERAL ELECTRIC COMPANY (US) 2011-03-01 US disclosed
US-20090149654-A1 INTERMEDIATES FOR FLUORINATED TETRABENAZINE CARBINOL COMPOUNDS IMAGING AGENTS AND PROBES GENERAL ELECTRIC COMPANY (US) 2009-06-11 US disclosed
US-20090143587-A1 INTERMEDIATES FOR ALPHA-FLUOROALKYL TETRABENAZINE AND DIHYDROTETRABENAZINE IMAGING AGENTS AND PROBES GENERAL ELECTRIC COMPANY (US) 2009-06-04 US disclosed
US-20090142265-A1 ALPHA-FLUOROALKYL TETRABENAZINE AND DIHYDROTETRABENAZINE IMAGING AGENTS AND PROBES GENERAL ELECTRIC COMPANY (US) 2009-06-04 US disclosed
US-20090110636-A1 FLUORINATED DIHYDROTETRABENAZINE ETHER IMAGING AGENTS AND PROBES GENERAL ELECTRIC COMPANY (US) 2009-04-30 US disclosed
US-20090111990-A1 INTERMEDIATES FOR FLUORINATED DIHYDROTETRABENAZINE ETHER IMAGING AGENTS AND PROBES GENERAL ELECTRIC COMPANY (US) 2009-04-30 US disclosed