SCHEMBL12295674

SCHEMBL12295674

CCc1nc2cc(Cl)ccn2c1C(=O)NCc1ccc(-c2ccc(F)cc2C)cc1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 7/20 0.62
CYP2C19 P33261 5/20 0.62
CYP3A4 P08684 3/20 0.62
WDR5 P61964 11/20 0.42
GCGR P47871 1/20 0.40
ENPP2 Q13822 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16704325 0.93 CYP2C9 (0.61) CYP2C9CYP2C19CYP3A4ENPP2
SCHEMBL12295286 0.92 CYP2C9 (0.63) CYP2C9CYP2C19CYP3A4WDR5GCGR
SCHEMBL12295470 0.90 CYP2C9 (0.71) CYP2C9CYP2C19CYP3A4ENPP2
SCHEMBL12294582 0.88 CYP2C9 (0.58) CYP2C9CYP2C19CYP3A4ENPP2
SCHEMBL12296316 0.88 CYP2C9 (0.55) CYP2C9CYP2C19CYP3A4ENPP2
SCHEMBL12294629 0.85 CYP2C9 (0.63) CYP2C9CYP2C19CYP3A4ENPP2
SCHEMBL12294627 0.85 CYP2C9 (0.70) CYP2C9CYP2C19CYP3A4ENPP2
SCHEMBL12295285 0.84 CYP2C9 (0.62) CYP2C9CYP2C19CYP3A4GCGR
SCHEMBL12295420 0.84 CYP2C9 (0.73) CYP2C9CYP2C19CYP3A4
SCHEMBL2402348 0.84 CYP2C9 (0.68) CYP2C9CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011113606-A1 ANTI-INFECTIVE COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2011-09-22 WO disclosed