⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909114 | 0.69 | — | — | |
| SCHEMBL12774875 | 0.67 | — | — | |
| SCHEMBL15940521 | 0.67 | — | — | |
| SCHEMBL19886832 | 0.67 | — | — | |
| SCHEMBL8882266 | 0.67 | — | — | |
| SCHEMBL14052202 | 0.62 | — | — | |
| SCHEMBL19622241 | 0.62 | — | — | |
| SCHEMBL15268205 | 0.62 | — | — | |
| SCHEMBL13956304 | 0.59 | — | — | |
| SCHEMBL1833000 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2717916-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2013082196-A1 | bFGF-POLYMER CONJUGATES, METHODS FOR MAKING THE SAME AND APPLICATIONS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | WO | disclosed |
| WO-2012171020-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012158795-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2012-11-22 | — | — | WO | disclosed |
| WO-2011120053-A1 | MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2011-09-29 | — | — | WO | disclosed |
| US-20080014149-A1 | Methods and Compositions for Imaging and Biomedical Applications | EMORY UNIVERSITY | 2008-01-17 | — | — | US | disclosed |