Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798268 | 0.94 | CFTR (1.00) | CFTR | |
| SCHEMBL29699242 | 0.94 | CFTR (1.00) | CFTR | |
| SCHEMBL29798093 | 0.94 | CFTR (1.00) | CFTR | |
| SCHEMBL2372654 | 0.94 | CFTR (1.00) | CFTR | |
| SCHEMBL17103827 | 0.79 | CFTR (0.73) | CFTR | |
| SCHEMBL12295840 | 0.77 | CFTR (0.87) | CFTR | |
| SCHEMBL22791077 | 0.75 | CFTR (0.87) | CFTR | |
| SCHEMBL2372600 | 0.74 | CFTR (1.00) | CFTR | |
| SCHEMBL2371649 | 0.74 | CFTR (1.00) | CFTR | |
| SCHEMBL2372606 | 0.74 | CFTR (1.00) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113894-A1 | PYRIDINE AND PYRAZINE DERIVATIVE FOR THE TREATMENT OF CF | NOVARTIS AG (CH) | 2011-09-22 | — | — | WO | disclosed |