Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859138 | 0.91 | CYP2C19 (0.54) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| SCHEMBL2863159 | 0.91 | TDP1 (0.56) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| SCHEMBL4159314 | 0.83 | MAPK1 (0.48) | CYP2C19KDM4EMAPK1CYP1A2CYP2D6 | |
| SCHEMBL15859 | 0.83 | TDP1 (0.75) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| SCHEMBL419073 | 0.80 | — | — | |
| SCHEMBL26967080 | 0.80 | TDP1 (0.71) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| SCHEMBL5129514 | 0.80 | TDP1 (0.71) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| Ammonia Solution, Strong SCHEMBL7104676 | 0.80 | TDP1 (0.71) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| SCHEMBL5131831 | 0.80 | TDP1 (0.71) | TDP1PAOXCYP2C19CYP2C9KDM4E | |
| SCHEMBL15826250 | 0.79 | TDP1 (0.58) | TDP1PAOXCYP2C19CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313147-A1 | CHROMATOGRAPHIC MATERIAL FOR THE ABSORPTION OF PROTEINS AT PHYSIOLOGICAL IONIC STRENGTH | PALL CORPORATION (US) | 2011-12-22 | — | — | US | disclosed |
| US-8021889-B2 | Chromatographic material for the absorption of proteins at physiological ionic strength | PALL CORPORATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-20070151910-A1 | Chromatographic material for the absorption of proteins at physiological ionic strength | PALL CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313147-A1 | CHROMATOGRAPHIC MATERIAL FOR THE ABSORPTION OF PROTEINS AT PHYSIOLOGICAL IONIC STRENGTH | SLC7A1, MAX, STAMBP | TDP1 4536/4885PAOX 3959/4885CYP2C19 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.