SCHEMBL123018

SCHEMBL123018

FCOCC1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL415514 0.87 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL414804 0.83 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL19689426 0.83 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24183422 0.83 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24183351 0.83 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL12568988 0.80 KDM4E (0.40) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL415515 0.80 KDM4E (0.40) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL10447558 0.80 KDM4E (0.47) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL14585705 0.79 KDM4E (0.37) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24086890 0.78 KDM4E (0.39) KDM4EALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923035-B2 Method for producing organic electronic devices with bank structures, bank structures and electronic devices produced therewith MERCK PATENT GMBH (DE) 2018-03-20 US disclosed
US-9647222-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9328179-B2 Water soluble norbornene-type polymers and photoimageable compositions thereof PROMERUS, LLC (US) 2016-05-03 US disclosed
US-9261782-B2 Maleimide containing cycloolefinic polymers and applications thereof PROMERUS, LLC (US) 2016-02-16 US disclosed
US-20150372246-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES FLEXENABLE TECHNOLOGY LIMITED (GB) 2015-12-24 US disclosed
US-9175123-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-20150270318-A1 METHOD FOR PRODUCING ORGANIC ELECTRONIC DEVICES WITH BANK STRUCTURES, BANK STRUCTURES AND ELECTRONIC DEVICES PRODUCED THEREWITH MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
US-20140349233-A1 WATER SOLUBLE NORBORNENE-TYPE POLYMERS AND PHOTOIMAGEABLE COMPOSITIONS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2014-11-27 US disclosed
US-20140087293-A1 MALEIMIDE CONTAINING CYCLOOLEFINIC POLYMERS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2014-03-27 US disclosed
US-20130207091-A1 PLANARIZATION LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2013-08-15 US disclosed
US-20120056183-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed