Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 3/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559198 | 0.85 | CLK4 (0.73) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL28029638 | 0.84 | CLK4 (0.72) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL17864721 | 0.83 | DYRK1A (0.71) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL25269044 | 0.83 | CLK4 (0.70) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL31230014 | 0.83 | CLK4 (0.70) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL2666349 | 0.83 | CLK4 (0.70) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL27807278 | 0.82 | DYRK1A (0.69) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL27785384 | 0.82 | DYRK1A (0.69) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL30447335 | 0.81 | CLK4 (0.68) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL25260413 | 0.81 | CLK4 (0.68) | CLK4DYRK1ACYP19A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |
| US-8293715-B2 | 10a-Azalide compound crosslinked at 10a- and 12-positions | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| CN-101812022-B | Ortho-monovinylphenyl substituted compound of aryl pyrimidine and synthesizing method thereof | UNIV SHANGHAI | 2012-01-04 | — | — | CN | disclosed |
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| CN-101812022-A | Ortho-monovinylphenyl substituted compound of aryl pyrimidine and synthesizing method thereof | UNIV SHANGHAI | 2010-08-25 | — | — | CN | disclosed |
| CN-1046218-C | Process for the carbonylation of acetylenically unsaturated compounds | SHELL INT RESEARCH (NL) | 1999-11-10 | — | — | CN | disclosed |
| CN-1088851-A | The catalyst system that the carbonylation of acetylenically unsaturated compound is used | SHELL INT RESEARCH (NL) | 1994-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | DCLRE1A, AZI2, CHD9 | CLK4 4600/4885DYRK1A 3675/4885CYP19A1 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.