Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.62 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308 | 0.87 | HRH3 (0.66) | HRH3EGLN1EBPLIPE | |
| SCHEMBL6137 | 0.87 | HRH3 (0.66) | HRH3EGLN1EBPLIPE | |
| SCHEMBL1589768 | 0.87 | HRH3 (0.66) | HRH3EGLN1EBPLIPE | |
| SCHEMBL9671 | 0.87 | HRH3 (0.60) | HRH3EGLN1EBP | |
| SCHEMBL10149 | 0.86 | HRH3 (0.60) | HRH3EGLN1LIPE | |
| SCHEMBL1589959 | 0.86 | HRH3 (0.60) | HRH3EGLN1LIPE | |
| SCHEMBL10150 | 0.86 | HRH3 (0.60) | HRH3EGLN1LIPE | |
| SCHEMBL5536 | 0.86 | HRH3 (0.63) | HRH3EGLN1EBPLIPE | |
| SCHEMBL747761 | 0.85 | HRH3 (0.59) | HRH3EGLN1EBPLIPE | |
| SCHEMBL5842 | 0.84 | HRH3 (0.58) | HRH3EGLN1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045292-A1 | SPIRO-CONDENSED CYCLOHEXANE DERIVATIVES AS HSL INHIBITORS USEFUL FOR THE TREATMENT OF DIABETES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-21 | — | — | WO | disclosed |