SCHEMBL12304239

SCHEMBL12304239

CCCCCCN(CCCCCC)c1ccc2cc(-c3ccccc3)c(=O)oc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.58
RAB9A P51151 8/20 0.58
MAPT P10636 7/20 0.58
KDM4E B2RXH2 7/20 0.58
ALDH1A1 P00352 6/20 0.58
MEN1 O00255 5/20 0.58
KMT2A Q03164 5/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
HTT P42858 4/20 0.58
LMNA P02545 3/20 0.58
USP2 O75604 2/20 0.58
CYP19A1 P11511 3/20 0.57
NR1H4 Q96RI1 1/20 0.56
MIF P14174 1/20 0.51
MAOB P27338 2/20 0.50
CASP1 P29466 2/20 0.49
CASP7 P55210 2/20 0.49
HBB P68871 2/20 0.49
ATM Q13315 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14408379 0.89 MAPT (0.61) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL194256 0.85 CYP19A1 (0.79) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL13869318 0.85 CYP19A1 (0.70) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL14408354 0.84 MAPT (0.60) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL14252702 0.81 MAPT (0.51) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL2053260 0.80 PIK3CD (0.59) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL22551261 0.80 MAPT (0.80) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL5597069 0.80 CYP19A1 (0.70) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL13870232 0.80 CYP19A1 (0.73) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL13869334 0.80 CYP19A1 (0.55) NPC1RAB9AMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293150-B2 Near-infrared absorbing material FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8021573-B2 Oxidized N,N*-[-(4-amino)diphenyl]-p-phenylenediamine derivatives or dimmonium salt; di-benzoxazole or chromene derivative as luminescent agent; light resistance, discoloration inhibition; optical filters and recording media FUJIFILM CORPORATION (JP) 2011-09-20 US disclosed
US-7875215-B2 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-20100224839-A1 NEAR-INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-20080073626-A1 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080067479-A1 NEAR-INFRARED-ABSORBING MATERIAL AND NEAR-INFRARED-ABSORBING FILTER FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed