SCHEMBL1230668

SCHEMBL1230668

CCCCCCCCCC[Al].[HH].[HH]

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
DNM1 Q05193 9/20 0.50
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
EPHX1 P07099 1/20 0.50
LMNA P02545 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692784 1.00
SCHEMBL151385 1.00
SCHEMBL204094 1.00
SCHEMBL10834951 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL1232119 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL11589356 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL673791 1.00
SCHEMBL7644799 1.00
SCHEMBL1230666 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL1232228 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011016992-A2 POLYMERIC CHAIN TRANSFER/SHUTTLING AGENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO claimed
WO-2011016992-A2 POLYMERIC CHAIN TRANSFER/SHUTTLING AGENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO disclosed
EP-0432939-B1 Oil soluble amino-substituted polymers containing graft polymer segments derived form aromatic nitrogen-containing monomers EXXON CHEMICAL PATENTS INC (US) 1996-09-18 EP disclosed
EP-0594603-B1 NOVEL DISPERSANT VISCOSITY INDEX IMPROVER COMPOSITIONS EXXON CHEMICAL PATENTS INC (US) 1995-10-04 EP disclosed
US-5382632-A Ethylene-propylene-norbornene methylamine grafted with aniline EXXON CHEMICAL PATENTS INC. (US) 1995-01-17 US disclosed
US-5376728-A Oil-soluble, polyaniline-grafted addition polymers; electroconductivity; halogen-free; molding materials; thin films/electrical/ EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US disclosed
US-5376153-A Oil additive; dispersant, oxidation and wear resistance, flow control agent EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US disclosed
EP-0518949-B1 NOVEL HETEROCYCLIC NITROGEN COMPOUND MANNICH BASE DERIVATIVES OF AMINO-SUBSTITUTED POLYMERS FOR OLEAGINOUS COMPOSITIONS EXXON CHEMICAL PATENTS INC (US) 1994-06-22 EP disclosed
EP-0594603-A1 NOVEL DISPERSANT VISCOSITY INDEX IMPROVER COMPOSITIONS. EXXON CHEMICAL PATENTS INC (US) 1994-05-04 EP disclosed
US-5278241-A Catalytic grafting of aromatic amines onto amino polymers EXXON CHEMICAL PATENTS INC. (US) 1994-01-11 US disclosed
US-5278240-A Catalytic grafting of aromatic amines onto amino polymers EXXON CHEMICAL PATENTS INC. (US) 1994-01-11 US disclosed
US-5271856-A Heterocyclic nitrogen compound Mannich base derivatives of amino-substituted polymers for oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1993-12-21 US disclosed
US-5153282-A Preparation of polyolefin incorporating functional groups from masked functional group-containing monomers EXXON CHEMICAL PATENTS INC. (US) 1992-10-06 US disclosed
EP-0295076-B1 POLYOLEFINS INCORPORATING FUNCTIONAL GROUPS, MASKED FUNCTIONAL GROUP-CONTAINING MONOMERS, REACTION MIXTURES, AND METHODS FOR PREPARING SAME EXXON CHEMICAL PATENTS INC. (US) 1992-09-30 EP disclosed
WO-1991013953-A1 NOVEL DISPERSANT VISCOSITY INDEX IMPROVER COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 1991-09-19 WO disclosed
US-5030370-A Polymer of a metal-masked amino-substituted monomer and an alpha-olefin which was subsequently deashed EXXON CHEMICAL PATENTS INC. (US) 1991-07-09 US disclosed
EP-0432939-A2 Oil soluble amino-substituted polymers containing graft polymer segments derived form aromatic nitrogen-containing monomers EXXON CHEMICAL PATENTS INC. (US) 1991-06-19 EP disclosed
US-4987200-A METALLIZATION BEFORE POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1991-01-22 US disclosed
EP-0295076-A1 Polyolefins incorporating functional groups, masked functional group-containing monomers, reaction mixtures, and methods for preparing same EXXON CHEMICAL PATENTS INC. (US) 1988-12-14 EP disclosed