Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032599 | 0.86 | MEN1 (0.38) | HDAC6ALDH1A1 | |
| SCHEMBL22100792 | 0.84 | TAAR1 (0.40) | AOC3 | |
| SCHEMBL22100802 | 0.84 | TAAR1 (0.40) | AOC3 | |
| SCHEMBL28460556 | 0.84 | TAAR1 (0.40) | AOC3 | |
| SCHEMBL21848069 | 0.82 | CA1 (0.31) | — | |
| SCHEMBL21848070 | 0.82 | CA1 (0.31) | — | |
| SCHEMBL21848071 | 0.82 | CA1 (0.31) | — | |
| SCHEMBL25264993 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1 | |
| SCHEMBL25189956 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1 | |
| SCHEMBL25264994 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011022348-A1 | ETHYLENE DIAMINE MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-24 | — | — | WO | disclosed |