Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12100517 | 0.85 | BTK (0.61) | BTKTNK2 | |
| SCHEMBL169823 | 0.85 | BTK (0.61) | BTKTNK2 | |
| SCHEMBL122913 | 0.84 | BTK (0.60) | BTKTNK2 | |
| SCHEMBL122924 | 0.84 | BTK (0.61) | BTKTNK2 | |
| SCHEMBL167469 | 0.81 | BTK (0.64) | BTKTNK2 | |
| SCHEMBL176919 | 0.80 | BTK (0.66) | BTKTNK2 | |
| SCHEMBL123306 | 0.79 | BTK (0.64) | BTKTNK2 | |
| SCHEMBL124952 | 0.78 | BTK (0.66) | BTKTNK2 | |
| SCHEMBL124951 | 0.78 | BTK (0.66) | BTKTNK2 | |
| SCHEMBL169601 | 0.78 | BTK (0.53) | BTKTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424368-A1 | PYRROLOTRIAZINE COMPOUNDS | Locus Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126960-A1 | PYRROLOTRIAZINE COMPOUNDS | LOCUS PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | WO | disclosed |