Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 13/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2413776 | 0.97 | PPARA (0.38) | PPARASLC22A12PPARGPPARD | |
| SCHEMBL12320069 | 0.97 | PPARA (0.40) | PPARASLC22A12HCAR3EGLN1PPARG | |
| Trifluoroacetic Acid SCHEMBL2419293 | 0.93 | PPARA (0.38) | PPARASLC22A12PPARGPPARD | |
| SCHEMBL2413778 | 0.89 | PPARA (0.31) | PPARAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL12274371 | 0.89 | PPARA (0.41) | PPARASLC22A12PPARGPPARD | |
| SCHEMBL2412574 | 0.89 | PPARA (0.42) | PPARASLC22A12PPARGPPARD | |
| Hydrochloric Acid SCHEMBL2414406 | 0.88 | PPARA (0.41) | PPARASLC22A12PPARGPPARD | |
| SCHEMBL12274275 | 0.87 | PPARA (0.39) | PPARASLC22A12HCAR3PPARGPPARD | |
| SCHEMBL12273833 | 0.87 | PPARA (0.39) | PPARASLC22A12HCAR3PPARGPPARD | |
| Hydrochloric Acid SCHEMBL2413565 | 0.86 | PPARA (0.39) | PPARASLC22A12HCAR3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |