Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12324731 | 0.87 | PLA2G2C (0.39) | PLA2G2CPLA2G10CTSKFOLH1RIMKLA | |
| SCHEMBL21686230 | 0.87 | PLA2G2C (0.63) | PLA2G2CPLA2G10 | |
| SCHEMBL29880335 | 0.87 | PLA2G2C (0.63) | PLA2G2CPLA2G10 | |
| SCHEMBL17793286 | 0.87 | PLA2G2C (0.63) | PLA2G2CPLA2G10 | |
| SCHEMBL9127074 | 0.87 | PLA2G2C (0.63) | PLA2G2CPLA2G10 | |
| SCHEMBL28227548 | 0.85 | PLA2G2C (0.61) | PLA2G2CPLA2G10 | |
| SCHEMBL21800920 | 0.85 | PLA2G2C (0.61) | PLA2G2CPLA2G10 | |
| SCHEMBL24486692 | 0.84 | PLA2G2C (0.42) | PLA2G2CPLA2G10CTSKFOLH1RIMKLA | |
| SCHEMBL173035 | 0.84 | PLA2G2C (0.42) | PLA2G2CPLA2G10CTSKFOLH1RIMKLA | |
| SCHEMBL17813082 | 0.83 | PLA2G2C (0.46) | PLA2G2CPLA2G10CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119759-A1 | COMPOUNDS (CYSTEIN BASED LIPOPEPTIDES) AND COMPOSITIONS AS TLR2 AGONISTS USED FOR TREATING INFECTIONS, INFLAMMATIONS, RESPIRATORY DISEASES ETC. | IRM LLC (BM) | 2011-09-29 | — | — | WO | disclosed |