Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419233 | 0.89 | P2RX1 (0.60) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL14419569 | 0.86 | CA1 (0.51) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL14419662 | 0.82 | TMPRSS4 (0.50) | P2RX1CA1CA2TMPRSS4HPGD | |
| SCHEMBL14355587 | 0.82 | TMPRSS4 (0.64) | P2RX1P2RX4P2RX7TMPRSS4KMT2A | |
| SCHEMBL12328683 | 0.81 | POLB (0.52) | LMNAHTTMAPTSMN1; SMN2KMT2A | |
| SCHEMBL12328447 | 0.80 | P2RX1 (0.54) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL14419294 | 0.80 | P2RX1 (0.60) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL14419538 | 0.80 | HPGD (0.56) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL12328445 | 0.79 | TMPRSS4 (0.50) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL14419278 | 0.79 | KMT2A (0.50) | P2RX1P2RX4P2RX7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781600-B1 | BENZOIC ACID DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-09-28 | — | — | EP | disclosed |