⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925179 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL20295961 | 0.98 | HRH3 (1.00) | — | |
| Hydrochloric Acid SCHEMBL27914617 | 0.98 | HRH3 (1.00) | — | |
| Hydrochloric Acid SCHEMBL1369323 | 0.98 | HRH3 (1.00) | — | |
| Hydrochloric Acid SCHEMBL20295958 | 0.98 | HRH3 (1.00) | — | |
| SCHEMBL18682135 | 0.84 | HRH3 (0.72) | — | |
| SCHEMBL2736110 | 0.83 | — | — | |
| SCHEMBL12680071 | 0.81 | CYP3A4 (0.69) | — | |
| SCHEMBL12257052 | 0.80 | HRH3 (0.67) | — | |
| SCHEMBL23192818 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929203-A1 | DERIVATIVES OF AMPHOTERICIN B | Sfunga Therapeutics, Inc. (US) | 2021-12-29 | — | — | EP | disclosed |
| EP-3283171-B1 | DERIVATIVES OF AMPHOTERICIN B | SFUNGA THERAPEUTICS INC (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020228478-A1 | ANTI-TUMOR DIAZOBICYCLIC APOPTOSIS PROTEIN INHIBITOR | 南京华威医药科技集团有限公司 | 2020-11-19 | — | — | WO | disclosed |
| WO-2020154673-A1 | BIS(DIAZIRINE) DERIVATIVES AS PHOTO-CROSSSLINKER FOR TREATING CORNEAL ECTATIC DISORDERS | AVEDRO, INC. (US) | 2020-07-30 | — | — | WO | disclosed |
| WO-2019170051-A1 | DACOS TYPE NNRTIS AMINO ACID ESTER DERIVATIVE, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 云南大学 | 2019-09-12 | — | — | WO | disclosed |
| WO-2016168568-A1 | DERIVATIVES OF AMPHOTERICIN B | Revolution Medicines, Inc. (US) | 2016-10-20 | — | — | WO | disclosed |
| US-20160304548-A1 | Derivatives of Amphotericin B | ELION THERAPEUTICS, INC. | 2016-10-20 | — | — | US | disclosed |
| EP-2365050-B1 | DI-AMIDO GELLANT FOR USE IN CONSUMER PRODUCT COMPOSITIONS | PROCTER & GAMBLE (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-2365051-A1 | Fluid detergent compositions comprising a di-amido gellant, and process for making | The Procter & Gamble Company (US) | 2011-09-14 | — | — | EP | disclosed |
| EP-2365050-A1 | Di-amido gelaant for use in consumer product compositions | The Procter & Gamble Company (US) | 2011-09-14 | — | — | EP | disclosed |