Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CASR | P41180 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11470149 | 0.81 | GAA (0.68) | GAAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15678805 | 0.80 | CNR1 (0.55) | CNR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5846249 | 0.79 | KCNH2 (0.58) | CNR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3641265 | 0.77 | KCNH2 (0.69) | CNR1GAAKCNH2MEN1KMT2A | |
| SCHEMBL7166881 | 0.77 | GAA (0.62) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11479009 | 0.77 | GAA (0.57) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL15571714 | 0.76 | HPGD (0.72) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7390885 | 0.75 | KCNH2 (0.53) | CNR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11796932 | 0.75 | KCNH2 (0.76) | CNR1KCNH2MEN1KMT2ACASR | |
| SCHEMBL14754215 | 0.74 | GAA (0.68) | GAAMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366698-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | Galapagos SAS (FR) | 2011-09-21 | — | — | EP | disclosed |