Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 19/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12331192 | 0.93 | APP (0.51) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12233908 | 0.93 | APP (0.51) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12233450 | 0.87 | APP (0.51) | APPCYP3A4 | |
| SCHEMBL14768521 | 0.85 | APP (0.53) | APPCYP3A4 | |
| SCHEMBL14753072 | 0.83 | APP (0.45) | APPCYP3A4PSEN1PSEN2APH1B | |
| SCHEMBL14754610 | 0.82 | APP (0.62) | APPCYP3A4 | |
| SCHEMBL12331649 | 0.80 | APP (0.52) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12331514 | 0.79 | APP (0.45) | APPCYP3A4PSEN1PSEN2APH1B | |
| SCHEMBL14753312 | 0.79 | APP (0.51) | APPCYP3A4 | |
| SCHEMBL14755361 | 0.79 | APP (0.61) | APPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109657-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |