Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930757 | 0.86 | CHRM4 (0.70) | P2RY12TRPV1TSHRHSD17B10CHRM4 | |
| SCHEMBL13930741 | 0.86 | CHRM4 (0.56) | P2RY12TSHRHSD17B10CHRM4KIT | |
| SCHEMBL13548403 | 0.86 | P2RY12 (0.55) | P2RY12TSHRHSD17B10CHRM4KIT | |
| SCHEMBL12190509 | 0.84 | TSHR (0.53) | P2RY12TSHRHSD17B10CHRM4KIT | |
| SCHEMBL12214313 | 0.84 | KDM4E (0.58) | P2RY12TSHRHSD17B10CHRM4KIT | |
| SCHEMBL12190505 | 0.84 | GAA (0.64) | TRPV1HSD17B10CHRM4 | |
| SCHEMBL31298090 | 0.83 | KDM4E (0.66) | P2RY12HSD17B10CHRM4KITKDM4E | |
| SCHEMBL12190517 | 0.83 | GRM5 (0.58) | P2RY12TSHRHSD17B10CHRM4KIT | |
| SCHEMBL13377920 | 0.81 | CHRM4 (0.59) | P2RY12TRPV1CHRM4 | |
| SCHEMBL14423759 | 0.79 | P2RY12 (0.59) | P2RY12TRPV1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942106-B1 | Therapeutic agents useful for treating pain | EURO CELTIQUE SA (LU) | 2011-09-14 | — | — | EP | disclosed |