Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | CASR | P41180 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334454 | 0.91 | EPHX2 (0.59) | CNR1KMT2AEPHX2NPC1RAB9A | |
| SCHEMBL12335330 | 0.85 | CNR1 (0.67) | CNR1KMT2AEPHX2NPC1RAB9A | |
| SCHEMBL12336147 | 0.85 | EPHX2 (0.54) | CNR1KMT2AEPHX2NAMPTHRH3 | |
| SCHEMBL14324509 | 0.83 | CNR1 (0.65) | CNR1KMT2AEPHX2RAB9ANAMPT | |
| SCHEMBL2458026 | 0.83 | IKBKB (0.65) | CNR1KMT2AEPHX2SMN1; SMN2NAMPT | |
| SCHEMBL12334456 | 0.82 | CNR1 (0.63) | CNR1KMT2AEPHX2HRH3 | |
| SCHEMBL12335085 | 0.82 | NPC1 (0.56) | CNR1KMT2AEPHX2NPC1RAB9A | |
| SCHEMBL12335329 | 0.81 | CNR1 (0.64) | CNR1KMT2AEPHX2NPC1RAB9A | |
| SCHEMBL12336159 | 0.81 | EPHX2 (0.52) | CNR1KMT2AEPHX2SMN1; SMN2NAMPT | |
| Hydrochloric Acid SCHEMBL7077713 | 0.81 | EPHX1 (0.61) | KMT2AEPHX2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150353538-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | ALZHEIMER'S INSTITUTE OF AMERICA, INC. (US) | 2015-12-10 | — | — | US | disclosed |
| US-20120329786-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| WO-2011109441-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353538-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | NFATC1, CD47, CD4 | CNR1 968/4885KMT2A 3000/4885EPHX2 2024/4885 |
| US-20120329786-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | NFATC1, CD47, CD4 | CNR1 968/4885KMT2A 3000/4885EPHX2 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.