Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 10/20 | 0.39 |
| ▸ | CA9 | Q16790 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337474 | 0.81 | CA12 (0.40) | CA12CA9LMNACA2CA1 | |
| SCHEMBL11596428 | 0.76 | — | — | |
| SCHEMBL13289758 | 0.68 | — | — | |
| SCHEMBL30529047 | 0.66 | CA12 (0.62) | CA12CA9LMNATHRBALDH1A1 | |
| SCHEMBL5533698 | 0.65 | — | — | |
| SCHEMBL23026342 | 0.64 | CHRM3 (0.34) | CHRM3CA12CA9LMNACHRM2 | |
| SCHEMBL5902597 | 0.64 | — | — | |
| SCHEMBL4919714 | 0.64 | — | — | |
| SCHEMBL5798986 | 0.64 | — | — | |
| SCHEMBL6544936 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322949-A1 | Hydrogel Compositions and Methods of Preparation Thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-12-20 | — | — | US | disclosed |
| US-8263715-B2 | Hydrogel compositions and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110054064-A1 | Hydrogel Compositions and Methods of Preparation Thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-03-03 | — | — | US | disclosed |