⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394196 | 0.79 | — | — | |
| SCHEMBL11300509 | 0.77 | — | — | |
| SCHEMBL28004241 | 0.77 | MGAM (0.63) | — | |
| SCHEMBL2913707 | 0.77 | — | — | |
| SCHEMBL7937771 | 0.77 | MGAM (0.55) | — | |
| Ethylene SCHEMBL29245647 | 0.76 | MGAM (0.61) | — | |
| SCHEMBL23101892 | 0.75 | TSHR (0.68) | — | |
| SCHEMBL53913 | 0.75 | — | — | |
| SCHEMBL3441102 | 0.75 | MGAM (0.69) | — | |
| SCHEMBL2612190 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8747809-B2 | Single diastereomers of 4-fluoroglutamine and methods of their preparation and use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-06-10 | — | — | US | disclosed |
| US-8747809-B2 | Single diastereomers of 4-fluoroglutamine and methods of their preparation and use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-06-10 | — | — | US | disclosed |
| US-8747809-B2 | Single diastereomers of 4-fluoroglutamine and methods of their preparation and use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120288444-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS OF THEIR PREPARATION AND USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120288444-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS OF THEIR PREPARATION AND USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120288444-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS OF THEIR PREPARATION AND USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-11-15 | — | — | US | disclosed |
| EP-2464223-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS FOR THEIR PREPARATION AND USE | The Trustees Of The University Of Pennsylvania (US) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011020018-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS FO THEIR PREPARATION AND USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011020018-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS FO THEIR PREPARATION AND USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-17 | — | — | WO | disclosed |