Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340338 | 0.91 | MCHR1 (0.83) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL12339978 | 0.91 | MCHR1 (0.83) | MCHR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL12339973 | 0.91 | MCHR1 (0.83) | MCHR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL539304 | 0.91 | MCHR1 (1.00) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL12340391 | 0.90 | MCHR1 (0.82) | MCHR1KCNH2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2958017 | 0.90 | MCHR1 (0.82) | MCHR1KCNH2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2955497 | 0.90 | MCHR1 (0.82) | MCHR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL12339970 | 0.90 | MCHR1 (0.82) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL12340388 | 0.90 | MCHR1 (0.82) | MCHR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL2962727 | 0.90 | MCHR1 (0.98) | MCHR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268868-B2 | 5-pyridinone substituted indazoles | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-09-18 | — | — | US | disclosed |