Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.80 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116739 | 0.94 | HCRTR1 (0.84) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL12342143 | 0.91 | HCRTR1 (0.89) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL16638928 | 0.89 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118509 | 0.89 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116493 | 0.89 | HCRTR1 (0.85) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2120259 | 0.88 | HCRTR1 (0.87) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610647 | 0.87 | HCRTR1 (0.77) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2119220 | 0.87 | HCRTR1 (0.82) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2117040 | 0.86 | HCRTR1 (0.82) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2119127 | 0.86 | HCRTR1 (0.87) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268848-B2 | Cyclopropane compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |