Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL29214721 | 1.00 | TSHR (0.89) | — | |
| Monoethanolamine SCHEMBL8339880 | 0.94 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL1331364 | 0.94 | — | — | |
| Monoethanolamine SCHEMBL4937454 | 0.94 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL14675689 | 0.94 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL10941117 | 0.94 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL29663853 | 0.94 | — | — | |
| Monoethanolamine SCHEMBL1644 | 0.94 | — | — | |
| Monoethanolamine SCHEMBL1332111 | 0.94 | — | — | |
| Monoethanolamine SCHEMBL2351509 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023179110-A1 | METHOD FOR SYNTHESIZING POLYETHYLENE POLYAMINE UNDER CATALYSIS | 中国科学院大连化学物理研究所 | 2023-09-28 | — | — | WO | claimed |
| US-11359281-B2 | Selective deposition of SiCON by plasma ALD | APPLIED MATERIALS, INC. (US) | 2022-06-14 | — | — | US | claimed |
| CN-113321219-A | Preparation method of spherical silicon micropowder | 刘亚 | 2021-08-31 | — | — | CN | claimed |
| US-20210230747-A1 | SELECTIVE DEPOSITION OF SICON BY PLAMA ALD | APPLIED MATERIALS, INC. (US) | 2021-07-29 | — | — | US | claimed |
| CN-108704155-A | A kind of lemon ordor removing lotion and preparation method thereof | 安徽中弘科技发展有限公司 | 2018-10-26 | — | — | CN | claimed |
| CN-108380192-A | A kind of compound bamboo charcoal powder of colloidal sol and preparation method thereof | 安徽中弘科技发展有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-108047626-A | A kind of expanded graphite crosslinking conductive material and preparation method thereof | 温州市赢创新材料技术有限公司 | 2018-05-18 | — | — | CN | claimed |
| US-20030153787-A1 | Esters of alkyl or alkenyl succinic acids with polyalkylene oxide derivatives of polyhydroxyl compounds have very useful thickening and or dispersant properties; cosmetics; detergent for shampoos, particularly for baby shampoos; emulsifiers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2003-08-14 | — | — | US | claimed |
| US-20020013494-A1 | SURFACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2002-01-31 | — | — | US | claimed |
| EP-0963245-A1 | SURFACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-12-15 | — | — | EP | claimed |
| WO-1998037957-A1 | SURFACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-09-03 | — | — | WO | claimed |
| US-4605770-A | Noncyclic polyalkylene polyamines by the reaction of an alkanolamine compound and an alkyleneamine compound in the presence of a Group IIA or Group IIIB metal acid phosphate catalyst | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-08-12 | — | — | US | claimed |
| EP-0149811-A2 | Production of noncyclic polyalkylene polyamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-07-31 | — | — | EP | claimed |
| WO-2023179110-A1 | METHOD FOR SYNTHESIZING POLYETHYLENE POLYAMINE UNDER CATALYSIS | 中国科学院大连化学物理研究所 | 2023-09-28 | — | — | WO | disclosed |
| CN-113321219-B | Preparation method of spherical silicon micropowder | 刘亚 | 2022-11-01 | — | — | CN | disclosed |
| US-11359281-B2 | Selective deposition of SiCON by plasma ALD | APPLIED MATERIALS, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| EP-0073520-B1 | PREPARATION OF POLYALKYLENE POLYAMINES FROM AMMONIA, ALKYLENEAMINE AND ALKANOLAMINE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-01-15 | — | — | EP | disclosed |
| EP-0149811-A2 | Production of noncyclic polyalkylene polyamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-07-31 | — | — | EP | disclosed |
| US-4394524-A | Preparation of polyalkylene polyamines from ammonia, alkyleneamine, and alkanolamine | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0073520-A1 | Preparation of polyalkylene polyamines from ammonia, alkyleneamine and alkanolamine | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1983-03-09 | — | — | EP | disclosed |