Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12336296 | 0.86 | CHKA (0.35) | SMN1; SMN2RAB9AALDH1A1HSD17B10NPC1 | |
| SCHEMBL12336247 | 0.85 | PDGFRB (0.35) | SMN1; SMN2RAB9AALDH1A1TP53KDM4E | |
| SCHEMBL12336255 | 0.84 | PDGFRB (0.33) | SMN1; SMN2RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL14949266 | 0.84 | PDGFRB (0.40) | RAB9ANPC1TP53KDM4EMAPT | |
| SCHEMBL12336257 | 0.83 | PDGFRB (0.39) | SMN1; SMN2RAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL12336573 | 0.83 | PDGFRB (0.34) | NUDT1RAB9AALDH1A1NPC1TP53 | |
| SCHEMBL14949693 | 0.82 | PDGFRB (0.35) | SMN1; SMN2MAPTSCN9AGAAPDGFRB | |
| SCHEMBL12336534 | 0.82 | PDGFRB (0.32) | SCN9APDGFRBKITPDGFRACDK11B | |
| SCHEMBL17339720 | 0.82 | KDM4E (0.30) | KDM4EPDGFRBKITPDGFRACDK11B | |
| SCHEMBL626064 | 0.82 | PDGFRB (0.53) | ALDH1A1KDM4EMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097594-A2 | THERAPEUTIC METHODS AND COMPOSITIONS INVOLVING ALLOSTERIC KINASE INHIBITION | KINAGEN, INC. (US) | 2011-08-11 | — | — | WO | disclosed |