Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL10976494 | 1.00 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL6666925 | 1.00 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL6657462 | 0.98 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL10399350 | 0.98 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Azelaic Acid SCHEMBL10982150 | 0.98 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Azelaic Acid SCHEMBL10980744 | 0.98 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL344766 | 0.98 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Octanedioate SCHEMBL29093966 | 0.98 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Terephthalic Acid SCHEMBL3334284 | 0.96 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL29026189 | 0.96 | CA12 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3694944-B1 | PROTECTIVE FILMS MADE OF POLYOLEFIN SUPPORT MATERIAL, PRIMER AND RADIATION-CROSSLINKABLE HOT MELT ADHESIVE | BASF SE (DE) | 2024-04-24 | — | — | EP | claimed |
| CN-111108166-B | Protective film made of a polyolefin support material, a primer and a radiation-crosslinkable hot-melt adhesive | 巴斯夫欧洲公司 | 2022-07-12 | — | — | CN | claimed |
| US-20200270487-A1 | PROTECTIVE FILMS MADE OF POLYOLEFIN SUPPORT MATERIAL, PRIMER AND RADIATION-CROSSLINKABLE HOT MELT ADHESIVE | BASF SE (DE) | 2020-08-27 | — | — | US | claimed |
| CN-111108166-A | Protective film made of a polyolefin support material, a primer and a radiation-crosslinkable hot-melt adhesive | 巴斯夫欧洲公司 | 2020-05-05 | — | — | CN | claimed |
| US-9669610-B2 | Use of aqueous polyurethane dispersions for laminating molded articles | BASF SE (DE) | 2017-06-06 | — | — | US | claimed |
| EP-2914642-B1 | USE OF AQUEOUS POLYURETHANE DISPERSIONS FOR LAMINATING MOLDED ARTICLES | BASF SE (DE) | 2017-01-18 | — | — | EP | claimed |
| EP-2788447-B1 | USE OF AQUEOUS POLYURETHANE DISPERSIONS FOR COMPOSITE FILM LAMINATION | BASF SE (DE) | 2015-09-16 | — | — | EP | claimed |
| US-20150239222-A1 | USE OF AQUEOUS POLYURETHANE DISPERSIONS FOR LAMINATING MOLDED ARTICLES | BASF SE (DE) | 2015-08-27 | — | — | US | claimed |
| US-20130149510-A1 | USE OF AQUEOUS POLYURETHANE DISPERSIONS FOR COMPOSITE FOIL LAMINATION | BASF SE (DE) | 2013-06-13 | — | — | US | claimed |
| US-RE34730-E | Polyurethane resins in water-dilutable basecoats having low flash and quick-drying characteristics | BASF CORPORATION, INMONT DIVISION (US) | 1994-09-13 | — | — | US | claimed |
| US-4182898-A | POLYURETHANE ELASTOMERS OF GOOD PHYSICAL PROPERTIES | ANDERSON DEVELOPMENT COMPANY (US) | 1980-01-08 | — | — | US | claimed |
| US-4054614-A | Water soluble polyester coating compositions | CELANESE CORPORATION (US) | 1977-10-18 | — | — | US | claimed |
| EP-3694944-B1 | PROTECTIVE FILMS MADE OF POLYOLEFIN SUPPORT MATERIAL, PRIMER AND RADIATION-CROSSLINKABLE HOT MELT ADHESIVE | BASF SE (DE) | 2024-04-24 | — | — | EP | disclosed |
| US-20240124663-A1 | Multilayer Composites of Printed Films | COVESTRO DEUTSCHLAND AG (DE) | 2024-04-18 | — | — | US | disclosed |
| CN-115124967-B | Epoxy modified vegetable oil-based bi-component polyurethane laminating adhesive and preparation method and application thereof | 广东天龙油墨有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-4294635-A1 | MULTILAYER COMPOSITES OF PRINTED FILMS | Covestro Deutschland AG (DE) | 2023-12-27 | — | — | EP | disclosed |
| EP-0084364-A1 | Polyurethane adhesive compositions | Takeda Chemical Industries, Ltd. (JP) | 1983-07-27 | — | — | EP | disclosed |
| EP-0068454-A1 | Composition for polyurethane resins and production of the resins | Takeda Chemical Industries, Ltd. (JP) | 1983-01-05 | — | — | EP | disclosed |
| US-4182898-A | POLYURETHANE ELASTOMERS OF GOOD PHYSICAL PROPERTIES | ANDERSON DEVELOPMENT COMPANY (US) | 1980-01-08 | — | — | US | disclosed |
| US-4061618-A | Process for preparing stable polyurethane latices | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |