Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1236430 | 0.93 | SYK (0.80) | SYK | |
| SCHEMBL10322744 | 0.91 | SYK (1.00) | SYK | |
| SCHEMBL1236076 | 0.90 | SYK (1.00) | SYK | |
| SCHEMBL1236192 | 0.90 | SYK (1.00) | SYK | |
| SCHEMBL1235617 | 0.84 | SYK (1.00) | SYK | |
| SCHEMBL1234111 | 0.84 | SYK (1.00) | SYK | |
| SCHEMBL1236625 | 0.83 | SYK (1.00) | SYK | |
| SCHEMBL1235632 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL1234998 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL1235193 | 0.79 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459558-A2 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2012-06-06 | — | — | EP | claimed |
| WO-2011014795-A2 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-02-03 | — | — | WO | claimed |