SCHEMBL12371263

SCHEMBL12371263

CCOCCOCCCN1CCCC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 8/20 0.49
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
SLC6A2 P23975 2/20 0.46
HRH1 P35367 2/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2C P18825 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KCNH2 Q12809 1/20 0.46
CACNA1C Q13936 1/20 0.46
SCN5A Q14524 1/20 0.46
CHRM4 P08173 1/20 0.45
HTR2C P28335 1/20 0.45
HTR7 P34969 1/20 0.45
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
ALDH1A1 P00352 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20333631 0.98 HRH3 (0.51) HRH3KDM4EHTTSLC6A2HRH1
SCHEMBL20332769 0.96 HRH3 (0.49) HRH3KDM4EHTTSLC6A2HRH1
SCHEMBL1161076 0.96 HRH3 (0.48) HRH3KDM4ESLC6A2HRH1CHRM2
SCHEMBL1162928 0.94 HRH3 (0.52) HRH3SLC6A2HRH1CHRM2ADRA2C
SCHEMBL21348358 0.92 KDM4E (0.47) HRH3KDM4EHTTSLC6A2HRH1
SCHEMBL24792370 0.91 HRH3 (0.43) HRH3SLC6A2HRH1CHRM2ADRA2C
SCHEMBL3312950 0.91 KDM4E (0.54) HRH3KDM4EHTTHRH1ALDH1A1
SCHEMBL12371261 0.91 KDM4E (0.54) HRH3KDM4EHTTHRH1ALDH1A1
SCHEMBL12371262 0.91 KDM4E (0.54) HRH3KDM4EHTTHRH1ALDH1A1
SCHEMBL20333182 0.90 HRH3 (0.48) HRH3KDM4EHTTSLC6A2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110202328-A1 System for the determination of selective absorbent molecules through predictive correlations EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-08-18 US disclosed
US-20110202328-A1 System for the determination of selective absorbent molecules through predictive correlations EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-08-18 US disclosed