SCHEMBL12373438

SCHEMBL12373438

O=C(Nc1ccc(-n2ccccc2=O)cc1F)[C@H]1C[C@H]1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030240 1.00 F10 (0.63) F10
SCHEMBL12374765 0.89 F10 (0.65) F10
SCHEMBL1026919 0.89 F10 (0.65) F10
SCHEMBL8261774 0.86 F10 (0.84) F10
SCHEMBL1030154 0.86 F10 (0.84) F10
SCHEMBL4447429 0.84 F10 (0.83) F10
SCHEMBL1082257 0.82 F10 (0.81) F10
SCHEMBL2253925 0.82 F10 (0.85) F10
SCHEMBL1027621 0.82 F10 (0.85) F10
SCHEMBL2251421 0.82 F10 (0.85) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110195997-A1 Dicarboxamide Derivatives ZBINDEN KATRIN GROEBKE 2011-08-11 US disclosed
WO-2007122104-A1 DICARBOXAMIDE DERIVATIVES F. HOFFMANN - LA ROCHE AG (CH) 2007-11-01 WO disclosed
US-20070249683-A1 Dicarboxamide derivatives HOFFMANN-LA ROCHE INC. 2007-10-25 US disclosed
US-20070249683-A1 Dicarboxamide derivatives HOFFMANN-LA ROCHE INC. 2007-10-25 US disclosed
EP-1847537-A1 Dicarboxamide derivatives F. HOFFMANN-LA ROCHE AG (CH) 2007-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195997-A1 Dicarboxamide Derivatives F12, F2, F3 F10 9/4885
US-20070249683-A1 Dicarboxamide derivatives F12, F2, F3 F10 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.