Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373822 | 0.91 | S1PR1 (0.46) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL12160954 | 0.87 | S1PR1 (0.59) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL12373817 | 0.86 | CNR1 (0.51) | S1PR1S1PR3CNR1CCR2 | |
| SCHEMBL2279361 | 0.86 | S1PR1 (0.51) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL12373849 | 0.85 | S1PR1 (0.47) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL2278141 | 0.85 | S1PR1 (0.48) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL12373819 | 0.85 | S1PR1 (0.49) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL12373842 | 0.84 | S1PR1 (0.47) | S1PR1S1PR3CYP2C19CYP2D6CNR1 | |
| SCHEMBL12373790 | 0.84 | S1PR1 (0.52) | S1PR1S1PR3CNR1CCR2 | |
| SCHEMBL2279119 | 0.84 | S1PR1 (0.43) | S1PR1S1PR3CYP2C19CYP2D6CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994204-B2 | Binding inhibitor of sphingosine-1-phosphate | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994204-B2 | Binding inhibitor of sphingosine-1-phosphate | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | S1PR1, S1PR3, S1PR2 | S1PR1 1/4885S1PR3 2/4885CYP2C19 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.