Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696070 | 1.00 | DPP4 (0.44) | DPP4GAADPP7EPHX1KCNH2 | |
| SCHEMBL15129485 | 1.00 | DPP4 (0.44) | DPP4GAADPP7EPHX1KCNH2 | |
| Hydrochloric Acid SCHEMBL3222770 | 0.98 | DPP4 (0.42) | DPP4GAADPP7EPHX1KCNH2 | |
| Hydrochloric Acid SCHEMBL3222764 | 0.98 | DPP4 (0.42) | DPP4GAADPP7EPHX1KCNH2 | |
| SCHEMBL27570839 | 0.98 | DPP4 (0.41) | DPP4GAADPP7EPHX1KCNH2 | |
| Ethyne SCHEMBL27874830 | 0.96 | DPP4 (0.41) | DPP4GAADPP7EPHX1KCNH2 | |
| Hydrochloric Acid SCHEMBL6438617 | 0.96 | DPP4 (0.40) | DPP4GAADPP7EPHX1KCNH2 | |
| Hydrochloric Acid SCHEMBL27551179 | 0.96 | DPP4 (0.40) | DPP4GAADPP7EPHX1KCNH2 | |
| Formic Acid SCHEMBL18274671 | 0.93 | DPP4 (0.40) | DPP4GAADPP7EPHX1KCNH2 | |
| SCHEMBL14978004 | 0.90 | DPP4 (0.36) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371459-A1 | DIMERIC PEPTIDE INHIBITORS OF APOPTOSIS PROTEINS | Hepagene Therapeutics (HK) Limited (HK) | 2021-12-02 | — | — | US | disclosed |
| EP-2078007-B1 | IKK-BETA SERINE-THREONINE PROTEIN KINASE INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2011-08-31 | — | — | EP | disclosed |
| US-8003695-B2 | IKK-beta serine-threonine protein kinase inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2011-08-23 | — | — | US | disclosed |
| US-8003695-B2 | IKK-beta serine-threonine protein kinase inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2011-08-23 | — | — | US | disclosed |
| US-20100087515-A1 | IKK-BETA SERINE-THREONINE PROTEIN KINASE INHIBITORS | Chroma Terapeutics Ltd (GB) | 2010-04-08 | — | — | US | disclosed |
| US-20100087515-A1 | IKK-BETA SERINE-THREONINE PROTEIN KINASE INHIBITORS | Chroma Terapeutics Ltd (GB) | 2010-04-08 | — | — | US | disclosed |
| WO-2008053182-A1 | IKK-β SERINE-THREONINE PROTEIN KINASE INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371459-A1 | DIMERIC PEPTIDE INHIBITORS OF APOPTOSIS PROTEINS | BIRC2, BIRC5, BIRC3 | DPP4 1412/4885GAA 4075/4885DPP7 427/4885 |
| US-20100087515-A1 | IKK-BETA SERINE-THREONINE PROTEIN KINASE INHIBITORS | IRAK3, IKBKE, IRAK1 | DPP4 3419/4885GAA 3885/4885DPP7 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.