Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2277095 | 0.86 | ABCG2 (0.47) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2278993 | 0.86 | ABCG2 (0.47) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2283911 | 0.86 | ABCG2 (0.47) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2277100 | 0.86 | ABCG2 (0.47) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2278989 | 0.86 | ABCG2 (0.47) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2283908 | 0.86 | ABCG2 (0.47) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2284220 | 0.85 | ABCG2 (0.46) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2279715 | 0.85 | ABCG2 (0.46) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2277045 | 0.85 | ABCG2 (0.46) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA | |
| SCHEMBL2279708 | 0.85 | ABCG2 (0.46) | ABCG2SMN1; SMN2KDM4EALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |