SCHEMBL123756

SCHEMBL123756

Nc1ccc([N+](=O)[O-])cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.74
THRB P10828 1/20 0.74
GPR35 Q9HC97 3/20 0.64
TDP1 Q9NUW8 6/20 0.61
ALDH1A1 P00352 7/20 0.59
CYP3A4 P08684 4/20 0.59
TSHR P16473 3/20 0.59
TP53 P04637 1/20 0.59
HPGD P15428 1/20 0.59
MAPK1 P28482 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ALOX15 P16050 2/20 0.56
ERN1 O75460 1/20 0.53
HTT P42858 1/20 0.53
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
GFER P55789 1/20 0.51
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29835045 1.00 GAA (0.74) GAATHRBGPR35TDP1ALDH1A1
SCHEMBL19950700 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
SCHEMBL19950556 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
Hydrochloric Acid SCHEMBL11638072 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
SCHEMBL19950590 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
SCHEMBL19950669 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
SCHEMBL5123356 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
SCHEMBL19950502 0.98 GAA (0.71) GAATHRBGPR35TDP1ALDH1A1
Nitrogen SCHEMBL9958160 0.96 GAA (0.69) GAATHRBGPR35TDP1ALDH1A1
Sulfuric Acid SCHEMBL1881177 0.92 GAA (0.65) GAATHRBGPR35TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3718 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552774-B2 Method for preparing pyrotinib SUZHOU FUSHILAI PHARMACEUTICAL CO., LTD (CN) 2026-02-17 US claimed
EP-4633805-A1 PROCESS FOR PREPARING ALLYLIC ALCOHOL Firmenich SA (CH) 2025-10-22 EP claimed
CN-120040439-A Fluorescent probe based on 2-hydrazinopyridine modified aminobenzo phenoxazinone derivative and application thereof 中国烟草总公司安徽省公司 2025-05-27 CN claimed
CN-119899114-A Preparation method of 2-amino-5-nitrophenol impurity 九江善水科技股份有限公司 2025-04-29 CN claimed
CN-119553384-A Preparation method of antistatic modified nylon filament 广东金狮新材科技有限公司 2025-03-04 CN claimed
US-20240199881-A1 METAL COMPLEX DYES FOR INKJET PRINTING VIDEOJET TECHNOLOGIES INC. (US) 2024-06-20 US claimed
WO-2024126786-A1 PROCESS FOR PREPARING ALLYLIC ALCOHOL FIRMENICH SA (CH) 2024-06-20 WO claimed
EP-4381016-A1 METAL COMPLEX DYES FOR INKJET PRINTING Videojet Technologies Inc. (US) 2024-06-12 EP claimed
CN-118043407-A Metal complex dyes for inkjet printing 录象射流技术公司 2024-05-14 CN claimed
CN-115124452-B Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione 安庆朗坤药业有限公司 2024-03-01 CN claimed
EP-0166155-B1 2-ALKYLSULPHONYL-1,4-DIAMINOBENZENES, PROCESS FOR THEIR PREPARATION AND OXIDATIVE HAIR-DYEING COMPOSITIONS CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 1987-09-23 EP claimed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
US-4661114-A COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1987-04-28 US claimed
EP-0182187-A1 Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols Wella Aktiengesellschaft (DE) 1986-05-28 EP claimed
WO-1986002829-A1 OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1986-05-22 WO claimed
WO-1986000303-A1 TWO-ALKYL-SULPHONYL-1,4-DIAMINOBENZENES, PREPARATION THEREOF AND UTILISATION THEREOF WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
US-4473375-A COUPLER AND DEVELOPER FOR OXIDATION COLOR DYES WELLA AKTIENGESELLSCHAFT (DE) 1984-09-25 US claimed
US-4455364-A ETCHING RESISTANCE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-06-19 US claimed