SCHEMBL12376629

SCHEMBL12376629

CCN(CC)c1ccc(/N=N/c2[nH]nc(C(C)(C)C)c2C#N)c(NC(C)=O)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.32
HTT P42858 4/20 0.32
LMNA P02545 2/20 0.32
CDK2 P24941 1/20 0.32
GHSR Q92847 1/20 0.31
CSNK2A1 P68400 1/20 0.31
MEN1 O00255 5/20 0.31
KMT2A Q03164 5/20 0.31
ALDH1A1 P00352 4/20 0.31
POLB P06746 1/20 0.31
KDM4E B2RXH2 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 2/20 0.30
USP2 O75604 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9012967 0.82 MAPK8 (0.32) ALDH1A1HPGDMAPK8
SCHEMBL9012972 0.82 MAPK8 (0.32) ALDH1A1HPGDMAPK8
SCHEMBL12376631 0.81 HSD17B10 (0.33) MAPTHTTLMNAGHSRCSNK2A1
SCHEMBL13050476 0.81 MAPT (0.33) MAPTHTTLMNAGHSRCSNK2A1
SCHEMBL13050481 0.80 MAPT (0.32) MAPTHTTLMNAGHSRCSNK2A1
SCHEMBL13050482 0.80 MAPT (0.32) MAPTHTTLMNAGHSRCSNK2A1
SCHEMBL13050480 0.80 MAPT (0.34) MAPTHTTLMNAGHSRCSNK2A1
SCHEMBL13050485 0.80 MAPT (0.32) MAPTHTTLMNAGHSRCSNK2A1
SCHEMBL12376612 0.78 CSNK2A1 (0.32) MAPTCSNK2A1
SCHEMBL12376613 0.78 MAPT (0.31) MAPTCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7988776-B2 excellent spectral characteristics with sharp absorption, high fastness and excellent transfer sensitivity; pyrazolylazoaniline dye)characterized by having a sulfonyl group introduced as a 1-positioned substituent of pyrazole FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7838184-B2 Azo dye compound, coloring composition, ink sheet for thermal transfer recording, thermal transfer recording method, color toner, ink for inkjet, and color filter FUJIFILM CORPORATION (JP) 2010-11-23 US disclosed
US-20080248202-A1 COLORING COMPOSITION, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, COLOR FILTER, ADN AZO DYE FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20080081279-A1 AZO DYE COMPOUND, COLORING COMPOSITION, INK SHEET FOR THERMAL TRANSFER RECORDING, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INK FOR INKJET, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed