Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26280264 | 0.98 | TSHR (0.39) | TSHRKDM4ERECQLEPHX1HTR1B | |
| SCHEMBL27418647 | 0.93 | TSHR (0.35) | TSHRKDM4ERECQLEPHX1HTR1B | |
| SCHEMBL801169 | 0.89 | HTR1B (0.36) | TSHRKDM4ERECQLHTR1BHTR1D | |
| SCHEMBL13668379 | 0.89 | TSHR (0.40) | TSHRKDM4ERECQLHTR1BALDH1A1 | |
| SCHEMBL15713284 | 0.87 | TSHR (0.43) | TSHRKDM4ERECQLHTR1BALDH1A1 | |
| SCHEMBL15788000 | 0.84 | TSHR (0.38) | TSHRKDM4ERECQLHTR1BALDH1A1 | |
| SCHEMBL25828110 | 0.84 | TSHR (0.51) | TSHRKDM4ERECQLEPHX1ALDH1A1 | |
| SCHEMBL24763989 | 0.83 | CARM1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL19400017 | 0.83 | TSHR (0.35) | TSHRKDM4ERECQLEPHX1ALDH1A1 | |
| SCHEMBL23651532 | 0.83 | KDM4E (0.42) | TSHRKDM4ERECQLHTR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989586-B2 | Multiblock copolymers having improved mechanical properties | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-08-02 | — | — | US | disclosed |